| Registro completo |
| Provedor de dados: |
BABT
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| País: |
Brazil
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| Título: |
An aqueous extract of Vitex agnus castus alters the labeling of blood constituents with technetium-99m
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| Autores: |
Costa,Maria Regina de Macedo
Ribeiro,Camila Godinho
Santos-Filho,Sebastião David
Neves,Rosane de Figueiredo
Fonseca,Adenilson de Souza da
Bernardo-Filho,Mario
Catanho,Maria Teresa Jansem de Almeida
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| Data: |
2007-09-01
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| Ano: |
2007
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| Palavras-chave: |
Oxidant properties
Plasma proteins
Red blood cells
Technetium-99m
Vitex agnus-castus
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| Resumo: |
The development of experimental assays to study properties of herbal medicine is worthwhile. Vitex agnus castus (VAC) is utilized in popular medicine and some actions have been attributed to its extract. Blood cells (BC) and plasma proteins are labeled with technetium-99m (Tc-99m) and have been used in nuclear medicine, as in basic research. This procedure uses a reducing agent and stannous ion is utilized. There are reports that drugs can alter this labeling process. The aim of this work was to evaluate the influence of an aqueous extract of VAC on the labeling of blood constituents with Tc-99m. Blood was incubated with VAC, stannous chloride and Tc-99m, as sodium pertechnetate, and centrifuged. Samples of BC and plasma were separated, aliquots of BC and plasma were also precipitated with trichloroacetic acid to obtain soluble and insoluble fractions and the percentage of radioactivity (%ATI) was determined. The results show a statistical (p<0.05) alteration in the %ATI on blood compartments and on the insoluble fractions of plasma and BC. Probably, this extract would have chemical compounds with oxidant properties.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000600023
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| Editor: |
Instituto de Tecnologia do Paraná - Tecpar
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| Relação: |
10.1590/S1516-89132007000600023
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| Formato: |
text/html
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| Fonte: |
Brazilian Archives of Biology and Technology v.50 n.spe 2007
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| Direitos: |
info:eu-repo/semantics/openAccess
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